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AstraZeneca and Daiichi Sankyo announced new study results for their cancer drug datopotamab deruxtecan, showing a median survival of 15.6 months in patients with EGFR-mutated non-small cell lung cancer. Agenus plans to cut annual spending by 60% to focus on a late-stage cancer immunotherapy, while Amgen is investing $1 billion to expand its manufacturing in North Carolina. The U.S. Patent and Trademark Office has withdrawn a proposed rule aimed at reducing patent thickets, and Bluebird bio is executing a reverse stock split to comply with Nasdaq rules. Merus received FDA accelerated approval for zenocutuzumab, its first approved product.

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